Defining Oncology and Aging

Cancer survival rates decrease with age, in part because the efficacy of cancer therapies declines in older individuals. Chemotherapy and radiotherapy wreak havoc on the immune system, kill both healthy and cancerous cells alike and cause a buildup of cellular waste in the tissue. This residual waste needs to be either removed from the body or efficiently restored to its original biological function.

New technologies should emerge that address the latter by boosting the efficiency of DNA repair in critical cells following cancer treatment. Clinicians will welcome the development of new and innovative products which, while specifically killing cancer cells, will also promote 1) organ and tissue homeostasis by inducing organism overall regenerative potential, 2) angiogenesis, 3) interactions with the immune system and 4) protection against cell death and senescence.